Multifunctional Role of Polyvinylpyrrolidone in Pharmaceutical Formulations

Multifunctional Role of Polyvinylpyrrolidone in Pharmaceutical Formulations

Polyvinylpyrrolidone (PVP), a non-ionic polymer, has been employed in multifarious fields equivalent to paper, fibers and textiles, ceramics, and pharmaceutics resulting from its superior properties. Particularly in pharmacy, the properties of inertness, non-toxicity, and biocompatibility make it a flexible excipient for each standard formulations and novel managed or focused supply techniques, serving as a binder, coating agent, suspending agent, pore-former, solubilizer, stabilizer, and so on. PVP with completely different molecular weights (MWs) and concentrations is utilized in a wide range of formulations for various functions.

On this evaluate, PVP-related researches primarily in current 10 years have been collected, and its principal pharmaceutical functions have been summarized as follows: (i) bettering the bioavailability and stability of medicine, (ii) bettering the physicomechanical properties of preparations, (iii) adjusting the discharge charge of medicine, and (iv) prolonging the in vivo circulation time of liposomes. Most of those functions may very well be defined by the viscosity, solubility, hydrophilicity, and hydrogen bond-forming capability of PVP, and the particular motion mechanisms for every software have been additionally tried to determine.

The impact of PVP on bioavailability enchancment establishes it as a promising polymer within the rising managed or focused formulations, attracting rising curiosity on it. Subsequently, given its irreplaceability and large alternatives for future developments, this evaluate goals to offer an informative reference about present roles of PVP in pharmacy for readers. The understanding of drug-carrier interactions is important for the design and functions of metal-organic framework (MOF)-based drug supply techniques. Whereas such drug-carrier interactions will be basically completely different for MOFs with or with out defects.

On this work, we revealed that the defects in MOFs play a key function within the loading of many prescription drugs with phosphate or phosphonate teams. The host-guest interplay is dominated by the Coulombic attraction between phosphate/phosphonate teams and defect websites and it strongly enhances the loading capability. For comparable molecules and not using a phosphate/phosphonate group or for MOF with out defects, the loading capability is significantly diminished.

We employed solid-state nuclear magnetic resonance (NMR) and molecular simulations to elucidate the drug-carrier interplay mechanisms. By way of a synergistic mixture of experimental and theoretical analyses, the docking conformations of prescription drugs on the defects have been revealed. Subsequently, analysis on environmental conduct and management methods needs to be carried out together with assessing their persistent toxicity to establish potential human and ecological dangers.

Prevalence and unsafe impression of pharmaceutical and private care merchandise and antibiotics in atmosphere: A evaluate on rising contaminants

Antibiotic resistance is a world well being emergency linked to unrestrained use of pharmaceutical and private care merchandise (PPCPs) as prophylactic agent and therapeutic functions throughout varied industries. Prevalence of pharmaceuticalsare recognized in floor water, floor water, soils, and wastewater therapy vegetation (WWTPs) in ng/L to μg/L focus vary. The prevalence of natural compounds together with antimicrobial brokers, hormones, antibiotics, preservatives, disinfectants, artificial musks and so on. in atmosphere have posed critical well being considerations. The goal of this evaluate is to elucidate the main sources accountable for emergence of antibiotic resistance.

For this function, number of introductory sources and destiny of PPCPs in aquatic atmosphere together with human and veterinary wastes, aquaculture and agriculture associated wastes, and different anthropogenic actions have been mentioned. Moreover, genetic and enzymatic components accountable for switch and look of antibiotic resistance genes are introduced. Ecotoxicity of PPCPs has been studied in atmosphere in an effort to current danger imposed to human and ecological well being. As per printed literature experiences, the removing of antibiotics and associated traces being troublesome, {couples} the potential of emergence of antibiotic resistance and therefore sustainability in world water assets.

Multifunctional Role of Polyvinylpyrrolidone in Pharmaceutical Formulations

A Comparative Exploration of High quality Assurance Outcomes by the Third-Occasion Pharmaceutical Schooling Analysis in Japan

The Requirements for the Institution of Universities in Japan have been revised; subsequently, the variety of colleges or universities of pharmacy/pharmaceutical sciences elevated from 46 in 2002 to 74 in 2016.The pharmacy training programme was additionally modified from 4 to 6 years, which was carried out in 2006. On this examine, we offer the comparative outcomes of the primary cycle of the third-party accrediting group, the Japan Accreditation Board for Pharmaceutical Schooling (JABPE); Strategies: The outcomes of the primary cycle of all universities or colleges of pharmacy assessed by the JABPE from JABPE web site have been retrieved, and we collated and in contrast the outcomes based mostly on the 13 areas of the evaluation requirements; Outcomes:
In “enhancements”, the variety of public universities or colleges was lower than that of personal universities or colleges, and the variety of outdated non-public universities or colleges was additionally lower than the variety of new non-public universities or colleges in all evaluation areas.  These outcomes counsel that new universities or colleges established since 2003 haven’t but established their very own high quality assurance mechanism throughout the establishments. We have to evaluate the Japanese pharmacy training system or the evaluation standards for it to result in important change. The biomarkers of stress and toxicity have been evaluated in digestive gland, besides the lysosomal membrane stability measured in hemocytes.
Exposures brought on an oxidative stress as a result of decreased SOD and GST actions and GSH/GSSG ratio, elevated ranges of thiobarbituric acid-reactive substances and protein carbonyls (with some exceptions). Dc elevated cathepsin D exercise in lysosomes. Nf elevated lysosomal membrane stability and caspase-Three exercise. Rn brought on a dramatic distortion of metallo-thiolome resulting from elevated ranges of GSH and metallothionein-related thiols (MTSH) in addition to depletion of Zn, Cu and Cd within the composition of metallothioneins, and decreased Zn/Cu molar ratio within the tissue.

Caspase 14 p10 Antibody

20-abx008233
  • EUR 300.00
  • EUR 439.00
  • EUR 189.00
  • 100 ul
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  • 30 ul
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Caspase 5 p10 antibody

70R-49464 100 ul
EUR 244
Description: Purified Polyclonal Caspase 5 p10 antibody

Caspase 14 p10 antibody

70R-50903 100 ul
EUR 244
Description: Purified Polyclonal Caspase 14 p10 antibody

Cleaved Caspase-1 (Arg317) /P10 Antibody

AF4022 200ul
EUR 376
Description: Caspase 1 (p10,Cleaved-Arg317) Antibody detects endogenous levels of fragment of activated Caspase 1 resulting from cleavage adjacent to Arg317.

Caspase 1 (p10, Cleaved-Ala317) Antibody

20-abx015550
  • EUR 314.00
  • EUR 98.00
  • EUR 398.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg
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Anti-Caspase-1(P10)/CASP1 Antibody

PA1522 100ug/vial
EUR 334

Caspase 1 p10 Blocking Peptide

20-abx062325
  • EUR 272.00
  • EUR 411.00
  • 1 mg
  • 5 mg
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Caspase 14 (p10, Cleaved-Lys222) Antibody

20-abx015552
  • EUR 314.00
  • EUR 98.00
  • EUR 398.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg
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Caspase 5 (p10, Cleaved-Ser331) Antibody

20-abx015560
  • EUR 314.00
  • EUR 98.00
  • EUR 398.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg
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Anti-Caspase-3 (P10)/CASP3 Antibody

PA1302 100ug/vial
EUR 294

Anti-Caspase-3 (P10)/CASP3 Antibody

PA1302-2 100ug/vial
EUR 334

Anti-Caspase-8(P10)/CASP8 Antibody

PA1524 100ug/vial
EUR 334

Caspase 14 p10 Blocking Peptide

20-abx063778
  • EUR 272.00
  • EUR 411.00
  • 1 mg
  • 5 mg
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Caspase 5 p10 Blocking Peptide

20-abx062339
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  • EUR 411.00
  • 1 mg
  • 5 mg
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Cleaved Caspase-1 (Arg317) /P10 Blocking Peptide

AF4022-BP 1mg
EUR 195

Cleaved-Caspase-5 p10 (S331) Polyclonal Antibody

ES1020-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against Cleaved-Caspase-5 p10 (S331) from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA

Cleaved-Caspase-5 p10 (S331) Polyclonal Antibody

ES1020-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against Cleaved-Caspase-5 p10 (S331) from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA

Cleaved-Caspase-5 p10 (S331) Polyclonal Antibody

ABP50021-003ml 0.03ml
EUR 158
  • Immunogen information: Synthesized peptide derived from the C-terminal region of human Caspase-5 p10 at AA range: 290-370
  • Applications tips:
Description: A polyclonal antibody for detection of Cleaved-Caspase-5 p10 S331) from Human. This Cleaved-Caspase-5 p10 S331) antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human Caspase-5 p10 at AA range: 290-370

Cleaved-Caspase-5 p10 (S331) Polyclonal Antibody

ABP50021-01ml 0.1ml
EUR 289
  • Immunogen information: Synthesized peptide derived from the C-terminal region of human Caspase-5 p10 at AA range: 290-370
  • Applications tips:
Description: A polyclonal antibody for detection of Cleaved-Caspase-5 p10 S331) from Human. This Cleaved-Caspase-5 p10 S331) antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human Caspase-5 p10 at AA range: 290-370

Cleaved-Caspase-5 p10 (S331) Polyclonal Antibody

ABP50021-02ml 0.2ml
EUR 414
  • Immunogen information: Synthesized peptide derived from the C-terminal region of human Caspase-5 p10 at AA range: 290-370
  • Applications tips:
Description: A polyclonal antibody for detection of Cleaved-Caspase-5 p10 S331) from Human. This Cleaved-Caspase-5 p10 S331) antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human Caspase-5 p10 at AA range: 290-370

Cleaved-Caspase-5 p10 (S331) Polyclonal Antibody

40509-100ul 100ul
EUR 252

Cleaved-Caspase-5 p10 (S331) Polyclonal Antibody

40509-50ul 50ul
EUR 187

Anti-Cleaved-Caspase-5 p10 (S331) antibody

STJ90029 200 µl
EUR 197
Description: Rabbit polyclonal to Cleaved-Caspase-5 p10 (S331).

Anti-Caspase-1(P20)/CASP1 Antibody

PA1440-1 100ug/vial
EUR 294

Anti-Caspase 8/CASP8 Antibody

A00042-1 100ug/vial
EUR 294

Anti-Caspase-2/CASP2 Antibody

A02384-1 100ug/vial
EUR 334

Anti-Caspase 4/CASP4 Antibody

A02941-1 100ug/vial
EUR 334

Anti-Caspase-8 Rabbit Monoclonal Antibody

M00042-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal Caspase-8 Antibody. Validated in IF, WB and tested in Human.

Anti-Caspase-7 Rabbit Monoclonal Antibody

M01044-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal Caspase-7 Antibody. Validated in IP, WB and tested in Mouse, Rat.

Anti-Caspase-10 Rabbit Monoclonal Antibody

M02190-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal Caspase-10 Antibody. Validated in IP, WB and tested in Human.

Anti-Caspase-2 Rabbit Monoclonal Antibody

M02384-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal Caspase-2 Antibody. Validated in IF, IHC, WB and tested in Human, Mouse, Rat.

Anti-Caspase-6(P18)/CASP6 Antibody

PA1441-1 100ug/vial
EUR 334

Anti-Caspase-3(P17)/CASP3 Antibody

PA1961-1 100ug/vial
EUR 334

Caspase 1 Antibody

AF5418 200ul
EUR 304
Description: Caspase 1 Antibody detects endogenous levels of total Caspase 1.

Caspase 1 Antibody

ABF5418 100 ug
EUR 438

Caspase 1 antibody

70R-49451 100 ul
EUR 244
Description: Purified Polyclonal Caspase 1 antibody

Caspase 1 antibody

70R-49452 100 ul
EUR 244
Description: Purified Polyclonal Caspase 1 antibody

Caspase 1 antibody

70R-51474 100 ul
EUR 244
Description: Purified Polyclonal Caspase 1 antibody

Caspase 1 antibody

70R-35920 100 ug
EUR 327
Description: Rabbit polyclonal Caspase 1 antibody

Caspase 1 antibody

70R-31086 100 ug
EUR 327
Description: Rabbit polyclonal Caspase 1 antibody

Caspase 1 antibody

70R-31087 100 ug
EUR 327
Description: Rabbit polyclonal Caspase 1 antibody

Caspase 1 antibody

70R-31116 100 ug
EUR 327
Description: Rabbit polyclonal Caspase 1 antibody

caspase 1 Antibody

39310-100ul 100ul
EUR 390

Caspase-1 Antibody

48847-100ul 100ul
EUR 333

Caspase-1 Antibody

48847-50ul 50ul
EUR 239

Caspase-1 Antibody

3019-100
EUR 403

Caspase-1 Antibody

3019-30T
EUR 146

Caspase-1 Antibody

24290-100ul 100ul
EUR 390

Caspase-1 Antibody

24291-100ul 100ul
EUR 390

Caspase 1 antibody

20R-1427 100 ug
EUR 651
Description: Rabbit polyclonal Caspase 1 antibody

Caspase 1 Antibody

6687-100
EUR 338

Caspase 1 Antibody

6687-30T
EUR 146

Caspase 1 antibody

70R-13979 100 ug
EUR 322
Description: Affinity purified Rabbit polyclonal Caspase 1 antibody

Caspase 1 antibody

70R-14061 100 ug
EUR 322
Description: Affinity purified Rabbit polyclonal Caspase 1 antibody

Caspase 1 antibody

70R-11561 100 ug
EUR 527
Description: Rabbit polyclonal Caspase 1 antibody

Caspase 1 antibody

70R-15367 100 ug
EUR 327
Description: Rabbit polyclonal Caspase 1 antibody

Caspase 1 antibody

PAab10015 100 ug
EUR 386

3-D Life RGD Peptide

P10-3 3x 1 µmol
EUR 276

Anti-pro Caspase 9 Rabbit Monoclonal Antibody

M00080-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal pro Caspase 9 Antibody. Validated in WB and tested in Human.

Anti-pro Caspase 3 Rabbit Monoclonal Antibody

M00334-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal pro Caspase 3 Antibody. Validated in IP, IF, WB and tested in Human, Mouse.

Anti-Caspase-6 p18 Rabbit Monoclonal Antibody

M02631-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal Caspase-6 p18 Antibody. Validated in IP, WB and tested in Human.

Caspase Inhibitor Set I

A9901-1 1 Set
EUR 154

Caspase-3/7 Inhibitor

2780-1
EUR 153

Caspase-3/7 Inhibitor I

A1925-1 1 mg
EUR 148
Description: Caspase-3/7 inbibitor I is a potent, reversible, isatin sulfonamide-based inhibitor of caspase-3 (KI(app) = 60 nM) and caspase-7 (KI(app) = 170 nM). Is a weaker inhibitor of caspase-9 (Ki(app) = 3.1 mM).

Polyclonal Caspase-1 Antibody

APG02382G 0.1 mg
EUR 659
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Caspase-1 . This antibody is tested and proven to work in the following applications:

Caspase-1 Conjugated Antibody

C48847 100ul
EUR 397

anti- Caspase 1 antibody

FNab01284 100µg
EUR 548.75
  • Recommended dilution: WB: 1:500-1:2000,IHC: 1:20-1:200
  • Immunogen: caspase 1, apoptosis-related cysteine peptidase(interleukin 1, beta, convertase)
  • Uniprot ID: P29466
  • Gene ID: 834
  • Research Area: Metabolism
Description: Antibody raised against Caspase 1

anti- Caspase 1 antibody

FNab10015 100µg
EUR 548.75
  • Recommended dilution: WB: 1:200-1:2000
  • IHC: 1:50-1:500
  • Immunogen: caspase 1
  • Uniprot ID: P29466
  • Gene ID: 834
  • Research Area: Signal Transduction, Metabolism, Cardiovascular, Neuroscience
Description: Antibody raised against Caspase 1

Caspase-1 Polyclonal Antibody

ES1850-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against Caspase-1 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

Caspase-1 Polyclonal Antibody

ES1850-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against Caspase-1 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

Caspase-1 Polyclonal Antibody

ES7677-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against Caspase-1 from Human/Monkey. This antibody is tested and validated for WB, ELISA, WB, ELISA

Caspase-1 Polyclonal Antibody

ES7677-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against Caspase-1 from Human/Monkey. This antibody is tested and validated for WB, ELISA, WB, ELISA

Caspase-1 Polyclonal Antibody

ES8461-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against Caspase-1 from Human/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

Caspase-1 Polyclonal Antibody

ES8461-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against Caspase-1 from Human/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

Caspase 1 (CASP1) Antibody

20-abx109605
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Caspase-1 Polyclonal Antibody

ABP57468-003ml 0.03ml
EUR 158
  • Immunogen information: Synthesized peptide derived from Caspase-1 at AA range: internal
  • Applications tips:
Description: A polyclonal antibody for detection of Caspase-1 from Human, Rat. This Caspase-1 antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from Caspase-1 at AA range: internal

Caspase-1 Polyclonal Antibody

ABP57468-01ml 0.1ml
EUR 289
  • Immunogen information: Synthesized peptide derived from Caspase-1 at AA range: internal
  • Applications tips:
Description: A polyclonal antibody for detection of Caspase-1 from Human, Rat. This Caspase-1 antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from Caspase-1 at AA range: internal

Caspase-1 Polyclonal Antibody

ABP57468-02ml 0.2ml
EUR 414
  • Immunogen information: Synthesized peptide derived from Caspase-1 at AA range: internal
  • Applications tips:
Description: A polyclonal antibody for detection of Caspase-1 from Human, Rat. This Caspase-1 antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from Caspase-1 at AA range: internal

Caspase 1 (CASP1) Antibody

20-abx000918
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul
  • Shipped within 5-10 working days.

Caspase 1 (CASP1) Antibody

abx148921-100ug 100 ug
EUR 439
  • Shipped within 5-10 working days.

Caspase 1 (pS376) Antibody

abx148922-100ug 100 ug
EUR 439
  • Shipped within 5-10 working days.

Caspase-1 Polyclonal Antibody

ABP56678-003ml 0.03ml
EUR 158
  • Immunogen information: Synthesized peptide derived from the C-terminal region of human Caspase-1 at AA range: 270-350
  • Applications tips:
Description: A polyclonal antibody for detection of Caspase-1 from Human, Monkey. This Caspase-1 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human Caspase-1 at AA range: 270-350

Caspase-1 Polyclonal Antibody

ABP56678-01ml 0.1ml
EUR 289
  • Immunogen information: Synthesized peptide derived from the C-terminal region of human Caspase-1 at AA range: 270-350
  • Applications tips:
Description: A polyclonal antibody for detection of Caspase-1 from Human, Monkey. This Caspase-1 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human Caspase-1 at AA range: 270-350

Caspase-1 Polyclonal Antibody

ABP56678-02ml 0.2ml
EUR 414
  • Immunogen information: Synthesized peptide derived from the C-terminal region of human Caspase-1 at AA range: 270-350
  • Applications tips:
Description: A polyclonal antibody for detection of Caspase-1 from Human, Monkey. This Caspase-1 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human Caspase-1 at AA range: 270-350

Caspase 1 (CASP1) Antibody

abx037580-100ug 100 ug
EUR 391
  • Shipped within 5-10 working days.

Caspase 1 (CASP1) Antibody

abx038263-100ug 100 ug
EUR 391
  • Shipped within 5-10 working days.

Caspase 1 (CASP1) Antibody

20-abx100442
  • EUR 411.00
  • EUR 133.00
  • EUR 1149.00
  • EUR 565.00
  • EUR 314.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Caspase 1 (CASP1) Antibody

20-abx100443
  • EUR 411.00
  • EUR 133.00
  • EUR 1149.00
  • EUR 565.00
  • EUR 314.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Caspase 1 (CASP1) Antibody

20-abx100444
  • EUR 425.00
  • EUR 133.00
  • EUR 1177.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Caspase 1 (CASP1) Antibody

20-abx100445
  • EUR 439.00
  • EUR 133.00
  • EUR 1247.00
  • EUR 592.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Caspase 1 (CASP1) Antibody

20-abx100446
  • EUR 467.00
  • EUR 133.00
  • EUR 1358.00
  • EUR 648.00
  • EUR 356.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Caspase-1 Polyclonal Antibody

ABP50851-003ml 0.03ml
EUR 158
  • Immunogen information: Synthesized peptide derived from human Caspase-1 around the non-phosphorylation site of S376
  • Applications tips:
Description: A polyclonal antibody for detection of Caspase-1 from Human, Mouse, Rat. This Caspase-1 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Caspase-1 around the non-phosphorylation site of S376

Caspase-1 Polyclonal Antibody

ABP50851-01ml 0.1ml
EUR 289
  • Immunogen information: Synthesized peptide derived from human Caspase-1 around the non-phosphorylation site of S376
  • Applications tips:
Description: A polyclonal antibody for detection of Caspase-1 from Human, Mouse, Rat. This Caspase-1 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Caspase-1 around the non-phosphorylation site of S376

Caspase-1 Polyclonal Antibody

ABP50851-02ml 0.2ml
EUR 414
  • Immunogen information: Synthesized peptide derived from human Caspase-1 around the non-phosphorylation site of S376
  • Applications tips:
Description: A polyclonal antibody for detection of Caspase-1 from Human, Mouse, Rat. This Caspase-1 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Caspase-1 around the non-phosphorylation site of S376

Caspase 1 p20 Antibody

20-abx009515
  • EUR 300.00
  • EUR 439.00
  • EUR 189.00
  • 100 ul
  • 200 ul
  • 30 ul
  • Shipped within 5-10 working days.

Caspase 1 (CASP1) Antibody

20-abx009516
  • EUR 300.00
  • EUR 439.00
  • EUR 189.00
  • 100 ul
  • 200 ul
  • 30 ul
  • Shipped within 5-10 working days.

Caspase 1 (CASP1) Antibody

20-abx009517
  • EUR 300.00
  • EUR 439.00
  • EUR 189.00
  • 100 ul
  • 200 ul
  • 30 ul
  • Shipped within 5-10 working days.

Caspase 1 (CASP1) Antibody

20-abx007565
  • EUR 300.00
  • EUR 439.00
  • EUR 189.00
  • 100 ul
  • 200 ul
  • 30 ul
  • Shipped within 5-10 working days.

Caspase 1 (CASP1) Antibody

20-abx175717
  • EUR 1177.00
  • EUR 578.00
  • 1 mg
  • 200 ug
  • Please enquire.

Caspase 1 (CASP1) Antibody

20-abx322935
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug
  • Shipped within 5-10 working days.

Caspase 1 (CASP1) Antibody

20-abx323629
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug
  • Shipped within 5-10 working days.

Caspase 1 (CASP1) Antibody

20-abx324419
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug
  • Shipped within 5-10 working days.

Caspase 1 (CASP1) Antibody

20-abx325046
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug
  • Shipped within 5-10 working days.

Caspase 1 (CASP1) Antibody

20-abx328453
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug
  • Shipped within 5-10 working days.

Caspase 1 (CASP1) Antibody

20-abx339093
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul
  • Shipped within 5-10 working days.

Caspase 1 (CASP1) Antibody

20-abx301352
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Caspase 1 (CASP1) Antibody

abx231284-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

Caspase 1 (CASP1) Antibody

20-abx171602
  • EUR 815.00
  • EUR 425.00
  • 1 mg
  • 200 ug
  • Please enquire.

Caspase 1 (CASP1) Antibody

20-abx171603
  • EUR 871.00
  • EUR 453.00
  • 1 mg
  • 200 ug
  • Please enquire.

Anti-Caspase-1 Antibody

A00048 100ug
EUR 432
Description: Rabbit Polyclonal Caspase-1 Antibody. Validated in IP, IF, IHC, WB and tested in Human, Mouse, Rat.

Caspase 1 p20 antibody

70R-49453 100 ul
EUR 244
Description: Purified Polyclonal Caspase 1 p20 antibody

Cleaved-Caspase-1 Antibody

A1004-50
EUR 338

Caspase 1 antibody (Ser376)

70R-35444 100 ug
EUR 327
Description: Purified Rabbit polyclonal Caspase 1 antibody (Ser376)

Caspase 1 antibody (HRP)

60R-1915 100 ug
EUR 327
Description: Rabbit polyclonal Caspase 1 antibody (HRP)

Caspase 1 antibody (FITC)

60R-1916 100 ug
EUR 327
Description: Rabbit polyclonal Caspase 1 antibody (FITC)

Caspase 1 antibody (biotin)

60R-1917 100 ug
EUR 327
Description: Rabbit polyclonal Caspase 1 antibody (biotin)

Anti-Caspase 1 antibody

PAab01284 100 ug
EUR 386

Anti-Caspase-1 antibody

STJ90020 200 µl
EUR 197
Description: Rabbit polyclonal to Caspase-1.

Anti-Caspase-1 antibody

STJ92017 200 µl
EUR 197
Description: Rabbit polyclonal to Caspase-1.

Anti-Caspase-1 antibody

STJ98574 200 µl
EUR 197
Description: Caspase-1 is a protein encoded by the CASP1 gene which is approximately 45,1 kDa. Caspase-1 is localised to the cytoplasm. It is involved in amyotrophic lateral sclerosis, toll-like receptor signalling pathways, p53 signalling and the TNFR1 pathway. This protein falls under the the cysteine-aspartic acid protease family. upon activation It plays a central role in the execution-phase of cell apoptosis. These enzymes can be divided into initiators and effectors. The initiator isoforms are activated by, and interact with, upstream adaptor molecules. Caspase-1 is expressed mainly in the spleen and lung. Mutations in the CASP1 gene may result in shigellosis and cowpox. STJ98574 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of Caspase-1.

Anti-caspase-1 antibody

STJ16101311 100 µg
EUR 716

Anti-caspase-1 antibody

STJ16101447 100 µg
EUR 716

Caspase-3 Inhibitor, Ac-DMQD-CHO

B2161-1
EUR 137

Caspase-8 Inhibitor Z-IETD-FMK

B4096-.1 100 µl (2 mM)
EUR 195
Description: Z-IETD-FMK is an inhibitor of caspase 8 [1].Z-IETD-FMK inhibits T cell proliferation induced by PHA or anti-CD3 plus anti-CD28 without toxicity of resting T cells.

Caspase-9 Inhibitor Z-LEHD-FMK

B4573-.1 100 µl (2 mM)
EUR 195
Description: Z-LEHD-FMK is a specific and irreversible inhibitor of caspase-9 [1]. Caspase-9 is an initiator caspase and plays an important role in the mitochondrial death pathway.

Ac-DEVD-CHO, Caspase-3 Inhibitor

10404-1 1MG
EUR 125
Description: Minimum order quantity: 1 unit of 1MG

Caspase-3 Inhibitor Q-DEVD-OPh

1175-1
EUR 272

Caspase-8 Inhibitor, Q-IETD-OPh

1176-1
EUR 305

Caspase-9 Inhibitor, Q-LEHD-OPh

1177-1
EUR 294

Caspase-3 inhibitor, Z-DQMD-FMK

2782-1
EUR 142

House Dust Mite Der p10 Protein

abx061467-05mg 0.5 mg
EUR 1080
  • Shipped within 5-10 working days.

Recombinant Dust Mite Der p10 [His]

DAGA-3089 0.5 mg
EUR 1300

Pan-caspase inhibitor, Q-VD(OMe)-OPh

2787-1
EUR 262

Caspase 12 (Caspase 12) Antibody

20-abx007974
  • EUR 300.00
  • EUR 439.00
  • EUR 189.00
  • 100 ul
  • 200 ul
  • 30 ul
  • Shipped within 5-10 working days.

Caspase 12 (Caspase 12) Antibody

abx432451-200ul 200 ul
EUR 384
  • Shipped within 1-3 working days.

Caspase 12 (Caspase 12) Antibody

abx231286-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

Phospho-Caspase 1 (Ser376) Antibody

AF5438 200ul
EUR 304
Description: Caspase 1 (Phospho-Ser376) Antibody detects endogenous levels of total Caspase 1 (Phospho-Ser376).

Polyclonal CASP1 / Caspase 1 Antibody

APG02372G 0.05mg
EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human CASP1 / Caspase 1 . This antibody is tested and proven to work in the following applications:

Polyclonal Cleaved-Caspase-1 Antibody

APG02632G 0.05ml
EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Cleaved-Caspase-1 . This antibody is tested and proven to work in the following applications:

Caspase 1 (CASP1) Antibody (Biotin)

20-abx105219
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Caspase 1 (CASP1) Antibody (FITC)

20-abx106636
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Caspase 1 (CASP1) Antibody (HRP)

20-abx108053
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Caspase 1 (Cleaved-Asp210) Antibody

20-abx015540
  • EUR 314.00
  • EUR 98.00
  • EUR 398.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg
  • Shipped within 5-10 working days.

Caspase 1 (Cleaved-Asp210) Antibody

20-abx015541
  • EUR 314.00
  • EUR 98.00
  • EUR 398.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg
  • Shipped within 5-10 working days.

Caspase 1 (Phospho- Ser376) Antibody

ABF5438 100 ug
EUR 438

Caspase 1 (CASP1) Antibody (Biotin)

20-abx273481
  • EUR 509.00
  • EUR 258.00
  • EUR 1539.00
  • EUR 718.00
  • EUR 411.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-15 working days.

Caspase 1 (CASP1) Antibody (FITC)

20-abx273692
  • EUR 467.00
  • EUR 244.00
  • EUR 1358.00
  • EUR 648.00
  • EUR 356.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-15 working days.

Caspase 1 (CASP1) Antibody (HRP)

20-abx306366
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Caspase 1 (CASP1) Antibody (FITC)

20-abx306367
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Caspase 1 (CASP1) Antibody (Biotin)

20-abx306368
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Caspase 1 (CASP1) Antibody Pair

20-abx370417
  • EUR 1664.00
  • EUR 1066.00
  • 10 × 96 tests
  • 5 × 96 tests
  • Shipped within 5-15 working days.

Caspase 1 (CASP1) Antibody (Biotin)

20-abx272160
  • EUR 439.00
  • EUR 244.00
  • EUR 1261.00
  • EUR 606.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-15 working days.

Caspase 1 (CASP1) Antibody (Biotin)

20-abx272990
  • EUR 453.00
  • EUR 244.00
  • EUR 1288.00
  • EUR 620.00
  • EUR 342.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-15 working days.

Caspase 1 (CASP1) Antibody (Biotin)

20-abx273261
  • EUR 467.00
  • EUR 244.00
  • EUR 1344.00
  • EUR 634.00
  • EUR 356.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-15 working days.

Caspase 1 protein

30R-2404 25 units
EUR 375
Description: Purified recombinant Human Caspase 1 protein

Caspase 1 protein

30R-2413 25 units
EUR 295
Description: Purified recombinant Mouse Caspase 1 protein

anti-Caspase 1

YF-PA10676 100 ug
EUR 403
Description: Rabbit polyclonal to Caspase 1

Caspase-3 DEVD-R110 Fluorometric HTS Assay Kit

30009-1 1KIT
EUR 100
Description: Minimum order quantity: 1 unit of 1KIT

Caspase-8 IETD-R110 Fluorometric HTS Assay Kit

30012-1 1KIT
EUR 100
Description: Minimum order quantity: 1 unit of 1KIT

0.5-10UL CLEAR TIPS FOR P2/P10

T-300 1000/pk
EUR 219
Description: Non Filter Tips; Pipette Tips - Axygen

Cleaved Caspase-1 (Asp296) /P20 Antibody

AF4005 200ul
EUR 376
Description: Caspase 1 (p20,Cleaved-Asp296) Antibody detects endogenous levels of fragment of activated Caspase 1 resulting from cleavage adjacent to Asp296.

Polyclonal CASP1 / Caspase 1 Antibody (FITC)

APG02374G 0.05mg
EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human CASP1 / Caspase 1 (FITC). This antibody is tested and proven to work in the following applications:

Cleaved-Caspase-1 (D210) Polyclonal Antibody

ES7675-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against Cleaved-Caspase-1 (D210) from Human. This antibody is tested and validated for WB, ELISA, IF, IHC, WB, ELISA

Cleaved-Caspase-1 (D210) Polyclonal Antibody

ES7675-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against Cleaved-Caspase-1 (D210) from Human. This antibody is tested and validated for WB, ELISA, IF, IHC, WB, ELISA

Cleaved-Caspase-1 (M211) Polyclonal Antibody

ES7676-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against Cleaved-Caspase-1 (M211) from Human. This antibody is tested and validated for IHC, WB, ELISA
The actual toxicity of Rn was additionally attested by decreased lysosomal membrane stability and cholinesterase exercise. Canonical discriminant evaluation separated Rn-, Combine- and MixT-groups from the joint set of C-, Dc- and Nf-groups. Typically, compound-specific results have been expressed in U. tumidus responses to the mixtures, however in MixT-group some results have been specific or extraordinarily robust. Multi-marker method and integrative evaluation proved to be a useful gizmo for understanding potential future dangers to freshwater mussels below a mixture of xenobiotics and warming local weather.