Antibodies Elisa Kits Enzymes Exosomes Reagents Test Kits

New Insights and Current Approaches in Cardiac Hypertrophy Cell Culture

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Interlaboratory Validation of a Detection Methodology for Hepatitis E Virus RNA in Pig Liver

 

Background: Within the final years, the variety of notified hepatitis E circumstances in people has repeatedly elevated in Europe. Foodborne an infection with the zoonotic hepatitis E virus (HEV) genotype three is taken into account the most important reason for this illness. Undercooked liver and uncooked sausages containing the liver of pigs and wild boar are at excessive threat of containing HEV. Nonetheless, to date, no standardized technique for the detection of HEV-RNA in pig liver is out there.

 

Strategies: A world collaborative research on technique reproducibility involving 11 laboratories was carried out for an HEV-RNA detection technique, which consists of steps of pattern homogenization, RNA extraction and real-time RT-PCR detection, together with a course of management. Naturally contaminated pork liver samples containing two completely different quantities of HEV and a HEV-negative pork liver pattern have been examined by all laboratories utilizing the tactic.

 

Outcomes: Legitimate outcomes have been retrieved from 10 laboratories. A specificity of 100% and a sensitivity of 79% have been calculated for the tactic. False adverse outcomes have been solely retrieved from the pattern containing very low HEV quantities close to the detection restrict.

 

Conclusions: The outcomes present that the tactic is extremely particular, sufficiently delicate and sturdy to be used in numerous laboratories. The tactic can, due to this fact, be utilized to routine meals management in addition to in monitoring research.

Hepatitis A virus detection with PCR

 

chemexcil
chemexcil
Rat Sex Determining Region Y Box Protein 2 (SOX2) ELISA Kit
RDR-SOX2-Ra-48Tests 48 Tests
EUR 534
Rat Sex Determining Region Y Box Protein 2 (SOX2) ELISA Kit
RDR-SOX2-Ra-96Tests 96 Tests
EUR 742
SOX2 Antibody
25044-100ul 100ul
EUR 390
Sox2 antibody
20R-1751 100 ug
EUR 673
Description: Rabbit polyclonal Sox2 antibody
SOX2 antibody
20R-2500 50 ug
EUR 281
Description: Rabbit polyclonal SOX2 antibody
SOX2 Antibody
21425-100ul 100ul
EUR 252
SOX2 Antibody
21425-50ul 50ul
EUR 187
SOX2 Antibody
31128-100ul 100ul
EUR 252
SOX2 Antibody
31128-50ul 50ul
EUR 187
SOX2 antibody
70R-12166 100 ug
EUR 403
Description: Rabbit polyclonal SOX2 antibody
SOX2 antibody
70R-20460 50 ul
EUR 435
Description: Rabbit polyclonal SOX2 antibody
SOX2 Antibody
48128-100ul 100ul
EUR 333
SOX2 Antibody
48128-50ul 50ul
EUR 239
SOX2 antibody
38134-100ul 100ul
EUR 252
SOX2 antibody
10R-11127 100 ug
EUR 349
Description: Mouse monoclonal SOX2 antibody
SOX2 Antibody
43142-100ul 100ul
EUR 252
SOX2 Antibody
CSB-PA982860-
EUR 335
  • Form: liquid
  • Buffer: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibo
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Description: A polyclonal antibody against SOX2. Recognizes SOX2 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:1000
SOX2 Antibody
CSB-PA982860-100ul 100ul
EUR 316
  • Form: liquid
  • Buffer: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibo
  • Show more
Description: A polyclonal antibody against SOX2. Recognizes SOX2 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:1000
SOX2 Antibody
1-CSB-PA698932
  • EUR 317.00
  • EUR 244.00
  • 100ul
  • 50ul
  • Form: Liquid
  • Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Antigen affinity purification
Description: A polyclonal antibody against SOX2. Recognizes SOX2 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:2000-1:5000, IHC:1:25-1:100
SOX2 Antibody
DF6109 200ul
EUR 304
Description: SOX2 Antibody detects endogenous levels of total SOX2.
SOX2 Antibody
1-CSB-PA588368
  • EUR 317.00
  • EUR 244.00
  • 100ul
  • 50ul
  • Form: Liquid
  • Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Antigen affinity purification
Description: A polyclonal antibody against SOX2. Recognizes SOX2 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:15-1:50
SOX2 Antibody
1-CSB-PA16539A0Rb
  • EUR 317.00
  • EUR 335.00
  • 100ug
  • 50ug
  • Form: Liquid
  • Buffer: Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 >95%, Protein G purified
Description: A polyclonal antibody against SOX2. Recognizes SOX2 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200
Sox2 antibody
70R-SR013 100 ug
EUR 300
Description: Affinity purified Rabbit polyclonal Sox2 antibody
SOX2 antibody
70R-33158 100 ug
EUR 435
Description: Rabbit polyclonal SOX2 antibody
SOX2 antibody
70R-33160 100 ug
EUR 435
Description: Rabbit polyclonal SOX2 antibody
SOX2 Antibody
AF4010 200ul
EUR 376
Description: The antibody detects endogenous level of total SOX2 protein.
SOX2 Antibody
AF5140 200ul
EUR 304
Description: SOX2 Antibody detects endogenous levels of total SOX2.
SOX2 Antibody
BF0481 200ul
EUR 376
Description: SOX2 antibody detects endogenous levels of total SOX2.
SOX2 Antibody
1-CSB-PA022426GA01HU
  • EUR 597.00
  • EUR 333.00
  • 150ul
  • 50ul
  • Form: Liquid
  • Buffer: PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20oC, Avoid freeze / thaw cycles. Antigen Affinity Purified
Description: A polyclonal antibody against SOX2. Recognizes SOX2 from Human, Mouse, Rat, Zebrafish. This antibody is Unconjugated. Tested in the following application: ELISA, IF
sox2 Antibody
AF7950 200ul
EUR 376
Description: sox2 Antibody detects endogenous levels of sox2.
SOX2 Antibody
ABD6109 100 ug
EUR 438
SOX2 Antibody
ABF4010 100 ug
EUR 438
SOX2 Antibody
ABF5140 100 ug
EUR 438
SOX2 (Transcription Factor) (SOX2/1791) Antibody
BNUM1791-50 50uL
EUR 395
Description: Primary antibody against SOX2 (Transcription Factor) (SOX2/1791), 1mg/mL
SOX2 (Transcription Factor) (SOX2/1792) Antibody
BNUM1792-50 50uL
EUR 395
Description: Primary antibody against SOX2 (Transcription Factor) (SOX2/1792), 1mg/mL
SOX2 (Transcription Factor) (SOX2/1791) Antibody
BNUB1791-100 100uL
EUR 209
Description: Primary antibody against SOX2 (Transcription Factor) (SOX2/1791), Concentration: 0.2mg/mL
SOX2 (Transcription Factor) (SOX2/1791) Antibody
BNUB1791-500 500uL
EUR 458
Description: Primary antibody against SOX2 (Transcription Factor) (SOX2/1791), Concentration: 0.2mg/mL
SOX2 (Transcription Factor) (SOX2/1792) Antibody
BNUB1792-100 100uL
EUR 209
Description: Primary antibody against SOX2 (Transcription Factor) (SOX2/1792), Concentration: 0.2mg/mL
SOX2 (Transcription Factor) (SOX2/1792) Antibody
BNUB1792-500 500uL
EUR 458
Description: Primary antibody against SOX2 (Transcription Factor) (SOX2/1792), Concentration: 0.2mg/mL
SOX2 (Transcription Factor) (SOX2/1791) Antibody
BNC551791-100 100uL
EUR 199
Description: Primary antibody against SOX2 (Transcription Factor) (SOX2/1791),CF555 conjugate, Concentration: 0.1mg/mL
SOX2 (Transcription Factor) (SOX2/1791) Antibody
BNC551791-500 500uL
EUR 544
Description: Primary antibody against SOX2 (Transcription Factor) (SOX2/1791),CF555 conjugate, Concentration: 0.1mg/mL
SOX2 (Transcription Factor) (SOX2/1792) Antibody
BNC551792-100 100uL
EUR 199
Description: Primary antibody against SOX2 (Transcription Factor) (SOX2/1792),CF555 conjugate, Concentration: 0.1mg/mL
SOX2 (Transcription Factor) (SOX2/1792) Antibody
BNC551792-500 500uL
EUR 544
Description: Primary antibody against SOX2 (Transcription Factor) (SOX2/1792),CF555 conjugate, Concentration: 0.1mg/mL
SOX2 (Transcription Factor) (SOX2/1791) Antibody
BNC611791-100 100uL
EUR 199
Description: Primary antibody against SOX2 (Transcription Factor) (SOX2/1791),CF660R conjugate, Concentration: 0.1mg/mL
SOX2 (Transcription Factor) (SOX2/1791) Antibody
BNC611791-500 500uL
EUR 544
Description: Primary antibody against SOX2 (Transcription Factor) (SOX2/1791),CF660R conjugate, Concentration: 0.1mg/mL
SOX2 (Transcription Factor) (SOX2/1792) Antibody
BNC611792-100 100uL
EUR 199
Description: Primary antibody against SOX2 (Transcription Factor) (SOX2/1792),CF660R conjugate, Concentration: 0.1mg/mL
SOX2 (Transcription Factor) (SOX2/1792) Antibody
BNC611792-500 500uL
EUR 544
Description: Primary antibody against SOX2 (Transcription Factor) (SOX2/1792),CF660R conjugate, Concentration: 0.1mg/mL
SOX2 (Transcription Factor) (SOX2/1791) Antibody
BNC471791-100 100uL
EUR 199
Description: Primary antibody against SOX2 (Transcription Factor) (SOX2/1791),CF647 conjugate, Concentration: 0.1mg/mL
SOX2 (Transcription Factor) (SOX2/1791) Antibody
BNC471791-500 500uL
EUR 544
Description: Primary antibody against SOX2 (Transcription Factor) (SOX2/1791),CF647 conjugate, Concentration: 0.1mg/mL
SOX2 (Transcription Factor) (SOX2/1792) Antibody
BNC471792-100 100uL
EUR 199
Description: Primary antibody against SOX2 (Transcription Factor) (SOX2/1792),CF647 conjugate, Concentration: 0.1mg/mL
SOX2 (Transcription Factor) (SOX2/1792) Antibody
BNC471792-500 500uL
EUR 544
Description: Primary antibody against SOX2 (Transcription Factor) (SOX2/1792),CF647 conjugate, Concentration: 0.1mg/mL
SOX2 (Transcription Factor) (SOX2/1791) Antibody
BNC051791-100 100uL
EUR 199
Description: Primary antibody against SOX2 (Transcription Factor) (SOX2/1791),CF405M conjugate, Concentration: 0.1mg/mL
SOX2 (Transcription Factor) (SOX2/1791) Antibody
BNC051791-500 500uL
EUR 544
Description: Primary antibody against SOX2 (Transcription Factor) (SOX2/1791),CF405M conjugate, Concentration: 0.1mg/mL
SOX2 (Transcription Factor) (SOX2/1792) Antibody
BNC051792-100 100uL
EUR 199
Description: Primary antibody against SOX2 (Transcription Factor) (SOX2/1792),CF405M conjugate, Concentration: 0.1mg/mL
SOX2 (Transcription Factor) (SOX2/1792) Antibody
BNC051792-500 500uL
EUR 544
Description: Primary antibody against SOX2 (Transcription Factor) (SOX2/1792),CF405M conjugate, Concentration: 0.1mg/mL
SOX2 (Transcription Factor) (SOX2/1791) Antibody
BNC401791-100 100uL
EUR 199
Description: Primary antibody against SOX2 (Transcription Factor) (SOX2/1791),CF640R conjugate, Concentration: 0.1mg/mL
SOX2 (Transcription Factor) (SOX2/1791) Antibody
BNC401791-500 500uL
EUR 544
Description: Primary antibody against SOX2 (Transcription Factor) (SOX2/1791),CF640R conjugate, Concentration: 0.1mg/mL
SOX2 (Transcription Factor) (SOX2/1792) Antibody
BNC401792-100 100uL
EUR 199
Description: Primary antibody against SOX2 (Transcription Factor) (SOX2/1792),CF640R conjugate, Concentration: 0.1mg/mL
SOX2 (Transcription Factor) (SOX2/1792) Antibody
BNC401792-500 500uL
EUR 544
Description: Primary antibody against SOX2 (Transcription Factor) (SOX2/1792),CF640R conjugate, Concentration: 0.1mg/mL
SOX2 (Transcription Factor) (SOX2/1791) Antibody
BNC431791-100 100uL
EUR 199
Description: Primary antibody against SOX2 (Transcription Factor) (SOX2/1791),CF543 conjugate, Concentration: 0.1mg/mL
SOX2 (Transcription Factor) (SOX2/1791) Antibody
BNC431791-500 500uL
EUR 544
Description: Primary antibody against SOX2 (Transcription Factor) (SOX2/1791),CF543 conjugate, Concentration: 0.1mg/mL
SOX2 (Transcription Factor) (SOX2/1792) Antibody
BNC431792-100 100uL
EUR 199
Description: Primary antibody against SOX2 (Transcription Factor) (SOX2/1792),CF543 conjugate, Concentration: 0.1mg/mL
SOX2 (Transcription Factor) (SOX2/1792) Antibody
BNC431792-500 500uL
EUR 544
Description: Primary antibody against SOX2 (Transcription Factor) (SOX2/1792),CF543 conjugate, Concentration: 0.1mg/mL
SOX2 (Transcription Factor) (SOX2/1791) Antibody
BNC041791-100 100uL
EUR 199
Description: Primary antibody against SOX2 (Transcription Factor) (SOX2/1791),CF405S conjugate, Concentration: 0.1mg/mL
SOX2 (Transcription Factor) (SOX2/1791) Antibody
BNC041791-500 500uL
EUR 544
Description: Primary antibody against SOX2 (Transcription Factor) (SOX2/1791),CF405S conjugate, Concentration: 0.1mg/mL
SOX2 (Transcription Factor) (SOX2/1792) Antibody
BNC041792-100 100uL
EUR 199
Description: Primary antibody against SOX2 (Transcription Factor) (SOX2/1792),CF405S conjugate, Concentration: 0.1mg/mL
SOX2 (Transcription Factor) (SOX2/1792) Antibody
BNC041792-500 500uL
EUR 544
Description: Primary antibody against SOX2 (Transcription Factor) (SOX2/1792),CF405S conjugate, Concentration: 0.1mg/mL
SOX2 (Transcription Factor) (SOX2/1791) Antibody
BNC701791-100 100uL
EUR 199
Description: Primary antibody against SOX2 (Transcription Factor) (SOX2/1791),CF770 conjugate, Concentration: 0.1mg/mL
SOX2 (Transcription Factor) (SOX2/1791) Antibody
BNC701791-500 500uL
EUR 544
Description: Primary antibody against SOX2 (Transcription Factor) (SOX2/1791),CF770 conjugate, Concentration: 0.1mg/mL
SOX2 (Transcription Factor) (SOX2/1792) Antibody
BNC701792-100 100uL
EUR 199
Description: Primary antibody against SOX2 (Transcription Factor) (SOX2/1792),CF770 conjugate, Concentration: 0.1mg/mL
SOX2 (Transcription Factor) (SOX2/1792) Antibody
BNC701792-500 500uL
EUR 544
Description: Primary antibody against SOX2 (Transcription Factor) (SOX2/1792),CF770 conjugate, Concentration: 0.1mg/mL
SOX2 (Transcription Factor) (SOX2/1791) Antibody
BNC801791-100 100uL
EUR 199
Description: Primary antibody against SOX2 (Transcription Factor) (SOX2/1791),CF680 conjugate, Concentration: 0.1mg/mL
SOX2 (Transcription Factor) (SOX2/1791) Antibody
BNC801791-500 500uL
EUR 544
Description: Primary antibody against SOX2 (Transcription Factor) (SOX2/1791),CF680 conjugate, Concentration: 0.1mg/mL
SOX2 (Transcription Factor) (SOX2/1792) Antibody
BNC801792-100 100uL
EUR 199
Description: Primary antibody against SOX2 (Transcription Factor) (SOX2/1792),CF680 conjugate, Concentration: 0.1mg/mL
SOX2 (Transcription Factor) (SOX2/1792) Antibody
BNC801792-500 500uL
EUR 544
Description: Primary antibody against SOX2 (Transcription Factor) (SOX2/1792),CF680 conjugate, Concentration: 0.1mg/mL
SOX2 (Transcription Factor) (SOX2/1791) Antibody
BNCH1791-100 100uL
EUR 199
Description: Primary antibody against SOX2 (Transcription Factor) (SOX2/1791),Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL
SOX2 (Transcription Factor) (SOX2/1791) Antibody
BNCH1791-500 500uL
EUR 544
Description: Primary antibody against SOX2 (Transcription Factor) (SOX2/1791),Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL
SOX2 (Transcription Factor) (SOX2/1792) Antibody
BNCH1792-100 100uL
EUR 199
Description: Primary antibody against SOX2 (Transcription Factor) (SOX2/1792),Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL
SOX2 (Transcription Factor) (SOX2/1792) Antibody
BNCH1792-500 500uL
EUR 544
Description: Primary antibody against SOX2 (Transcription Factor) (SOX2/1792),Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL
SOX2 (Transcription Factor) (SOX2/1791) Antibody
BNCP1791-250 250uL
EUR 383
Description: Primary antibody against SOX2 (Transcription Factor) (SOX2/1791),PerCP conjugate, Concentration: 0.1mg/mL
SOX2 (Transcription Factor) (SOX2/1792) Antibody
BNCP1792-250 250uL
EUR 383
Description: Primary antibody against SOX2 (Transcription Factor) (SOX2/1792),PerCP conjugate, Concentration: 0.1mg/mL
SOX2 (Transcription Factor) (SOX2/1791) Antibody
BNCR1791-250 250uL
EUR 383
Description: Primary antibody against SOX2 (Transcription Factor) (SOX2/1791),RPE conjugate, Concentration: 0.1mg/mL
SOX2 (Transcription Factor) (SOX2/1792) Antibody
BNCR1792-250 250uL
EUR 383
Description: Primary antibody against SOX2 (Transcription Factor) (SOX2/1792),RPE conjugate, Concentration: 0.1mg/mL
SOX2 (Transcription Factor) (SOX2/1791) Antibody
BNC941791-100 100uL
EUR 199
Description: Primary antibody against SOX2 (Transcription Factor) (SOX2/1791),CF594 conjugate, Concentration: 0.1mg/mL
SOX2 (Transcription Factor) (SOX2/1791) Antibody
BNC941791-500 500uL
EUR 544
Description: Primary antibody against SOX2 (Transcription Factor) (SOX2/1791),CF594 conjugate, Concentration: 0.1mg/mL
SOX2 (Transcription Factor) (SOX2/1792) Antibody
BNC941792-100 100uL
EUR 199
Description: Primary antibody against SOX2 (Transcription Factor) (SOX2/1792),CF594 conjugate, Concentration: 0.1mg/mL
SOX2 (Transcription Factor) (SOX2/1792) Antibody
BNC941792-500 500uL
EUR 544
Description: Primary antibody against SOX2 (Transcription Factor) (SOX2/1792),CF594 conjugate, Concentration: 0.1mg/mL
SOX2 (Transcription Factor) (SOX2/1791) Antibody
BNCA1791-250 250uL
EUR 383
Description: Primary antibody against SOX2 (Transcription Factor) (SOX2/1791),APC conjugate, Concentration: 0.1mg/mL
SOX2 (Transcription Factor) (SOX2/1792) Antibody
BNCA1792-250 250uL
EUR 383
Description: Primary antibody against SOX2 (Transcription Factor) (SOX2/1792),APC conjugate, Concentration: 0.1mg/mL
SOX2 (Transcription Factor) (SOX2/1791) Antibody
BNCB1791-100 100uL
EUR 199
Description: Primary antibody against SOX2 (Transcription Factor) (SOX2/1791),Biotin conjugate, Concentration: 0.1mg/mL
SOX2 (Transcription Factor) (SOX2/1791) Antibody
BNCB1791-500 500uL
EUR 544
Description: Primary antibody against SOX2 (Transcription Factor) (SOX2/1791),Biotin conjugate, Concentration: 0.1mg/mL
SOX2 (Transcription Factor) (SOX2/1792) Antibody
BNCB1792-100 100uL
EUR 199
Description: Primary antibody against SOX2 (Transcription Factor) (SOX2/1792),Biotin conjugate, Concentration: 0.1mg/mL
SOX2 (Transcription Factor) (SOX2/1792) Antibody
BNCB1792-500 500uL
EUR 544
Description: Primary antibody against SOX2 (Transcription Factor) (SOX2/1792),Biotin conjugate, Concentration: 0.1mg/mL
SOX2 (Transcription Factor) (SOX2/1791) Antibody
BNC881791-100 100uL
EUR 199
Description: Primary antibody against SOX2 (Transcription Factor) (SOX2/1791),CF488A conjugate, Concentration: 0.1mg/mL
SOX2 (Transcription Factor) (SOX2/1791) Antibody
BNC881791-500 500uL
EUR 544
Description: Primary antibody against SOX2 (Transcription Factor) (SOX2/1791),CF488A conjugate, Concentration: 0.1mg/mL
SOX2 (Transcription Factor) (SOX2/1792) Antibody
BNC881792-100 100uL
EUR 199
Description: Primary antibody against SOX2 (Transcription Factor) (SOX2/1792),CF488A conjugate, Concentration: 0.1mg/mL

 

Lengthy noncoding RNA H19 regulates the therapeutic efficacy of mesenchymal stem cells in rats with extreme acute pancreatitis by sponging miR-138-5p and miR-141-3p

 

Background: Sufferers with extreme acute pancreatitis (SAP), which is characterised by excessive morbidity and mortality, account for an growing medical burden worldwide. We beforehand discovered that mesenchymal stem cells (MSCs) may attenuate SAP and that expression of lengthy noncoding RNA H19 (LncRNA H19) was upregulated in rats receiving MSCs. Within the current research, we investigated the mechanisms of LncRNA H19 regulating the therapeutic efficacy of MSCs within the alleviation of SAP.

 

Strategies: MSCs transfected with LncRNA H19 overexpression and knockdown plasmids have been intravenously injected into rats 12 h after sodium taurocholate (NaT) administration to induce SAP.

 

Outcomes: Overexpressing LncRNA H19 in MSCs considerably enhanced the anti-inflammatory capability of the MSCs, inhibited autophagy by way of promotion of focal adhesion kinase (FAK)-associated pathways, and facilitated cell proliferation by growing the extent of β-catenin in rats with SAP. LncRNA H19 functioned as a competing endogenous RNA by sponging miR-138-5p and miR-141-3p. Pulling down miR-138-5p in MSCs elevated the expression of protein tyrosine kinase 2 (PTK2, encoding FAK) to suppress autophagy, whereas downregulating miR-141-3p enhanced the extent of β-catenin to advertise cell proliferation.

 

Conclusions: In conclusion, LncRNA H19 successfully elevated the therapeutic efficacy of MSCs in rats with SAP by way of the miR-138-5p/PTK2/FAK and miR-141-3p/β-catenin pathways.

RNA-Binding Proteins in Most cancers: Sensible and Therapeutic Views

RNA-binding proteins (RBPs) crucially regulate gene expression by post-transcriptional regulation, akin to by modulating microRNA (miRNA) processing and the selection splicing, completely different polyadenylation, subcellular localization, stability, and translation of RNAs. Better than 1500 RBPs have been acknowledged to date, and loads of of them are acknowledged to be deregulated in most cancers. Alterations throughout the expression and localization of RBPs can have an effect on the expression ranges of oncogenes, tumor-suppressor genes, and genome stability-related genes.

RBP-mediated gene regulation may end up in quite a few cancer-related cellular phenotypes, akin to proliferation, apoptosis, angiogenesis, senescence, and epithelial-mesenchymal transition (EMT)/invasion/metastasis. This regulation could be associated to most cancers prognosis.

Thus, RBPs might be potential targets for the occasion of therapeutics for probably the most cancers remedy. On this overview, we describe the molecular options of RBPs, their roles in cancer-related cellular phenotypes, and quite a few approaches that might be used to concentrate on RBPs for many cancers remedy.

New Insights and Present Approaches in Cardiac Hypertrophy Cell Tradition, Tissue Engineering Fashions, and Novel Pathways Involving Non-Coding RNA

  • Cardiac hypertrophy is an ongoing medical problem, as threat components comparable to weight problems, smoking and growing age turn out to be extra widespread, which result in an growing prevalence of growing hypertrophy. Pathological hypertrophy is a maladaptive response to emphasize situations, comparable to strain overload, and contain quite a few modifications in mobile mechanisms, gene expression and pathway laws.
  • Though a number of essential pathways concerned within the reworking and hypertrophy course of have been recognized, additional analysis is required to realize a greater understanding and discover new and higher remedy choices.
  • Extra lately found pathways confirmed the involvement of a number of non-coding RNAs, together with micro RNAs (miRNAs), lengthy non-coding RNAs (lncRNAs), and round RNAs (circRNAs), which both promote or inhibit the reworking course of and pose a doable goal for novel remedy approaches.
  • In vitromodeling serves as a significant device for this additional pathway evaluation and remedy testing and has vastly improved over the latest years, offering a more cost effective and labor-intensive different to in vivo animal fashions.

 

Total Protein from Parkinson's Disease: Brain: Cerebellum

P1236039Par 1 mg
EUR 461
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Total Protein from Mouse Normal Tissue: Cerebellum

P1334039 1 mg
EUR 214
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Human Total PSA (t-PSA) ELISA Kit

PRB-5049-TOTAL 96 assays
EUR 572

Total Protein from Multiple Sclerosis Disease: Brain: Cerebellum

P1236039Msc 1 mg
EUR 461
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Total Protein from Progressive Supranuclear Palsy: Brain: Cerebellum

P1236039PSP 1 mg
EUR 556
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Cerebellum

TB19001 0.1 gm
EUR 396

Cerebellum

TB19007 5 Slides
EUR 422

Cerebellum

PC35103 Cerebellum
EUR 396

Cerebellum

PC35139 Cerebellum
EUR 396

Green RNA Lysis Kit 50

GREENE1-RNA 50pack
EUR 180
Description: Bead lysis kits for the homogenization of small, tough samples. Pack of 50, 1.5mL Eppendorf Safe-Lock tubes prefilled with beads. RNase free.

Green RNA Lysis Kit 250

GREENE5-RNA 250pack
EUR 571
Description: Bead lysis kits for the homogenization of small, tough samples. Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with beads. RNase free.

Navy RNA Lysis Kit 50

NAVYE1-RNA 50pack
EUR 198
Description: Bead lysis kits for the homogenization of large, tough samples. Pack of 50, 1.5mL Eppendorf Safe-Lock tubes prefilled with stainless steel beads. RNase free.

Navy RNA Lysis Kit 250

NAVYE5-RNA 250pack
EUR 651
Description: Bead lysis kits for the homogenization of large, tough samples. Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with stainless steel beads. RNase free.

YELLOW RNA Lysis Kit 50

YELLOWE1-RNA 50pack
EUR 192
Description: Bead lysis kits for the homogenization of small cell suspensions (ex - E. coli). Pack of 50, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

YELLOW RNA Lysis Kit 250

YELLOWE5-RNA 250pack
EUR 624
Description: Bead lysis kits for the homogenization of small cell suspensions (ex - E. coli). Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

Pink RNA Lysis Kit 50

PINKE1-RNA 50pack
EUR 178
Description: Bead lysis kits for the homogenization of small, soft or medium-tough samples. Pack of 50, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

Pink RNA Lysis Kit 250

PINKE5-RNA 250pack
EUR 561
Description: Bead lysis kits for the homogenization of small, soft or medium-tough samples. Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

Red RNA Lysis Kit 50

REDE1-RNA 50pack
EUR 192
Description: Bead lysis kits for the homogenization of large, soft or medium-tough samples. Pack of 50, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

Red RNA Lysis Kit 250

REDE5-RNA 250pack
EUR 622
Description: Bead lysis kits for the homogenization of large, soft or medium-tough samples. Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

RNA isolater Total RNA Extraction Reagent

R401-01 100 ml
EUR 133

5E GREEN RNA Lysis Kit 100

GREEN5E100-RNA 100pack
EUR 386
Description: Bead lysis kits for the homogenization of small, tough samples. Pack of 1000, 5mL Eppendorf Safe-Lock tubes prefilled with beads. RNase free.

5E GREEN RNA Lysis Kit 20

GREEN5E20-RNA 20pack
EUR 138
Description: Bead lysis kits for the homogenization of small, tough samples. Pack of 20, 5mL Eppendorf Safe-Lock tubes prefilled with beads. RNase free.

Green RINO RNA Lysis Kit 50

GREENR1-RNA 50pack
EUR 184
Description: Bead lysis kits for the homogenization of small, tough samples. Pack of 50, 1.5mL RINO screw-cap tubes prefilled with beads. RNase free.

Green RINO RNA Lysis Kit 250

GREENR5-RNA 250pack
EUR 587
Description: Bead lysis kits for the homogenization of small, tough samples. Pack of 250, 1.5mL RINO screw-cap tubes prefilled with beads. RNase free.

5E Navy RNA Lysis Kit 100

NAVY5E100-RNA 100pack
EUR 453
Description: Bead lysis kits for the homogenization of large, tough samples. Pack of 100, 5mL Eppendorf Safe-Lock tubes prefilled with stainless steel beads. RNase free.

5E Navy RNA Lysis Kit 20

NAVY5E20-RNA 20pack
EUR 153
Description: Bead lysis kits for the homogenization of large, tough samples. Pack of 20, 5mL Eppendorf Safe-Lock tubes prefilled with stainless steel beads. RNase free.

Navy RINO RNA Lysis Kit 50

NAVYR1-RNA 50pack
EUR 202
Description: Bead lysis kits for the homogenization of large, tough samples. Pack of 50, 1.5mL RINO screw-cap tubes prefilled with stainless steel beads. RNase free.

Navy RINO RNA Lysis Kit 250

NAVYR5-RNA 250pack
EUR 666
Description: Bead lysis kits for the homogenization of large, tough samples. Pack of 250, 1.5mL RINO screw-cap tubes prefilled with stainless steel beads. RNase free.

YELLOW RINO RNA Lysis Kit 50

YELLOWR1-RNA 50pack
EUR 199
Description: Bead lysis kits for the homogenization of small cell suspensions (ex - E. coli). Pack of 50, 1.5mL RINO screw-cap tubes prefilled with stabilized ceramic beads. RNase free.

YELLOW RINO RNA Lysis Kit 250

YELLOWR5-RNA 250pack
EUR 656
Description: Bead lysis kits for the homogenization of small cell suspensions (ex - E. coli). Pack of 250, 1.5mL RINO screw-cap tubes prefilled with stabilized ceramic beads. RNase free.

5E PINK RNA Lysis Kit 100

PINK5E100-RNA 100pack
EUR 380
Description: Bead lysis kits for the homogenization of small, soft or medium-tough samples. Pack of 100, 5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

5E PINK RNA Lysis Kit 20

PINK5E20-RNA 20pack
EUR 136
Description: Bead lysis kits for the homogenization of small, soft or medium-tough samples. Pack of 20, 5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

Pink RINO RNA Lysis Kit 50

PINKR1-RNA 50pack
EUR 181
Description: Bead lysis kits for the homogenization of small, soft or medium-tough samples. Pack of 50, 1.5mL RINO screw-cap tubes prefilled with stabilized ceramic beads. RNase free.

Pink RINO RNA Lysis Kit 250

PINKR5-RNA 250pack
EUR 576
Description: Bead lysis kits for the homogenization of small, soft or medium-tough samples. Pack of 250, 1.5mL RINO screw-cap tubes prefilled with stabilized ceramic beads. RNase free.

5E RED RNA Lysis Kit 100

RED5E100-RNA 100pack
EUR 429
Description: Bead lysis kits for the homogenization of large, soft or medium-tough samples. Pack of 100, 5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

5E RED RNA Lysis Kit 20

RED5E20-RNA 20pack
EUR 148
Description: Bead lysis kits for the homogenization of large, soft or medium-tough samples. Pack of 20, 5mL Eppendorf Safe-Lock tubes prefilled with stabilized ceramic beads. RNase free.

Red RINO RNA Lysis Kit 50

REDR1-RNA 50pack
EUR 195
Description: Bead lysis kits for the homogenization of large, soft or medium-tough samples. Pack of 50, 1.5mL RINO screw-cap tubes prefilled with stabilized ceramic beads. RNase free.

Red RINO RNA Lysis Kit 250

REDR5-RNA 250pack
EUR 638
Description: Bead lysis kits for the homogenization of large, soft or medium-tough samples. Pack of 250, 1.5mL RINO screw-cap tubes prefilled with stabilized ceramic beads. RNase free.

Total RNA Extraction Kit

K2014005 1 kit
EUR 344
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Total RNA Isolation Kit

P-9100 50 samples
EUR 347.25
Description: The best epigenetics products

Human Total PSA (t-PSA) ELISA Kit

PRB-5049-TOTAL-5 5 x 96 assays
EUR 2283

Total Protein from Human Adult Normal Tissue: Brain: Cerebellum (left)

P1234040 1 mg
EUR 214
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Total Protein from Human Adult Normal Tissue: Brain: Cerebellum (right)

P1234041 1 mg
EUR 214
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Total RNA from Rat Normal Tissue: Adipose

R1434003-50 50 ug
EUR 214
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Total RNA from Rat Normal Tissue: Bladder

R1434010-50 50 ug
EUR 303
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Total RNA from Rat Normal Tissue: Brain

R1434035-50 50 ug
EUR 152
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Total RNA from Rat Normal Tissue: Colon

R1434090-50 50 ug
EUR 152
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Total RNA from Rat Normal Tissue: Heart

R1434122-50 50 ug
EUR 152
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Total RNA from Rat Normal Tissue: Kidney

R1434142-50 50 ug
EUR 152
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Total RNA from Rat Normal Tissue: Liver

R1434149-50 50 ug
EUR 152
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Total RNA from Rat Normal Tissue: Lung

R1434152-50 50 ug
EUR 152
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Total RNA from Rat Normal Tissue: Ovary

R1434183-50 50 ug
EUR 296
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Total RNA from Rat Normal Tissue: Pancreas

R1434188-50 50 ug
EUR 296
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Total RNA from Rat Normal Tissue: Placenta

R1434200-50 50 ug
EUR 214
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Total RNA from Rat Normal Tissue: Rectum

R1434206-50 50 ug
EUR 214
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Total RNA from Rat Normal Tissue: Spleen

R1434246-50 50 ug
EUR 152
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Total RNA from Rat Normal Tissue: Stomach

R1434248-50 50 ug
EUR 214
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Total RNA from Rat Normal Tissue: Testis

R1434260-50 50 ug
EUR 152
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Total RNA from Rat Normal Tissue: Thymus

R1434264-50 50 ug
EUR 214
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Total RNA Isolation Kit II

FATRS--001 100 preps
EUR 308

Total RNA Isolation Kit II

FATRS--050 50 preps
EUR 216

Total RNA ExtractionMini KitAnimal Tissues

FYG301-50P 50 Preps Ask for price

Total RNA ExtractionMini KitAnimal Tissues

FYG302-100P 100 Preps Ask for price

Total RNA ExtractionMini KitAnimal Tissues

FYG302-300P 300 Preps Ask for price

Total RNA ExtractionMini KitPlant Tissues

FYG303-100P 100 Preps Ask for price

Total RNA ExtractionMini KitPlant Tissues

FYG303-300P 300 Preps Ask for price

Total RNA ExtractionMini KitPlant Tissues

FYG303-50P 50 Preps Ask for price

Total RNA Isolation Kit (Tissue)

P-9102 50 samples
EUR 347.25
Description: reagents widely cited

Total RNA Isolation Kit (Plant)

P-9104 50 samples
EUR 347.25
Description: kits suitable for this type of research

AnaPrep Total RNA Extraction Kit

Z1322015 1 kit (48 extractions) Including all required plastic disposables
EUR 308
Description: This kit is developped for our fully automated magnetic bead-based nucleic acid extraction platform which uses preprogrammed protocols and can process up to 12 samples simultaneously. With the AnaPrep 12 Extractor you will have the option to choose and work with a wide range of sample and reagent volumes. This sturdy, realiable and user-friendly machine will save you both time and expenses while ensuring consistently high quality performance and nucleic acids for your downstream applications.

Total RNA from Lupus: Colon

R1236090Lup-50 50 ug
EUR 351
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Total RNA from hypertension: Heart

R1236122Hd-2 50 ug
EUR 351
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Total RNA from Lupus: Kidney

R1236142Lup-50 50 ug
EUR 351
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Total RNA from Lupus: Liver

R1236149Lup-50 50 ug
EUR 351
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Total RNA from Lupus: Lung

R1236152Lup-50 50 ug
EUR 351
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Total RNA from Lupus: Pancreas

R1236188Lup-50 50 ug
EUR 351
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Total RNA from Lupus: Spleen

R1236246Lup-50 50 ug
EUR 351
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Total RNA from Lupus: Stomach

R1236248Lup-50 50 ug
EUR 351
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Total RNA from Lupus: Uterus

R1236274Lup-50 50 ug
EUR 351
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Rat Cerebellum Whole tissue lysate

RAL-1473 100ug
EUR 213

Total RNA from Rat Normal Tissue: Skeletal Muscle

R1434171-50 50 ug
EUR 152
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Total RNA from Rat Normal Tissue: Small Intestine

R1434226-50 50 ug
EUR 214
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Plant Total RNA Mini Kit (50prep)

FAPRK-001 50 preps
EUR 165

Plant Total RNA Mini Kit (100prep)

FAPRK-001-1 100 preps
EUR 216

Plant Total RNA Mini Kit (300prep)

FAPRK-001-2 300 preps
EUR 404

Plant Total RNA Maxi Kit (10prep)

FAPRK-002 10 preps
EUR 201

Plant Total RNA Maxi Kit (24prep)

FAPRK-002-1 24 preps
EUR 317

Tissue Total RNA Mini Kit (50prep)

FATRK-001 50 preps
EUR 165

Tissue Total RNA Mini Kit (100prep)

FATRK-001-1 100 preps
EUR 216

Tissue Total RNA Mini Kit (300prep)

FATRK-001-2 300 preps
EUR 404

Tissue Total RNA Maxi Kit (10prep)

FATRK-003 10 preps
EUR 201

Tissue Total RNA Maxi Kit (24prep)

FATRK-003-1 24 preps
EUR 317

Total RNA ExtractionMini KitBlood/Cultured Cell

FYG301-300P 300 Preps Ask for price

Broad Range Total RNA Isolation Kit

K1341050 1 kit
EUR 266
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Rapid Animal Total RNA Extraction Kit

AT4181 50Preps
EUR 88.06
  • Product category: Molecular Biology Kits/RNA - Extraction/Animal